First derived from hellebore roots in 1940, Resveratrol is a phytoalexin (plant antibiotic) that is produced naturally by many plants when they are under attack by pathogens like fungi or bacteria. It’s also naturally found in the skin of red grapes, but in quantities too small to fully confirm some experts’ claims that drinking wine can help combat cancer. There are, however, tests that show that drinking red wine can cut death rates by up to 40% per year.
Experiments done on the benefits of Resveratrol have shown positive results. It can lower blood sugar, increase cardiovascular function, and lengthen overall lifespan because its chemical structure 'activates' what is known as a 'longevity gene'. However, it must be pointed out that these experiments were conducted on rodents and cell cultures, not on humans.
It also seems to have a weighty effect on genes, as it can determine whether or not certain genes are turned off or on through a process called descetylation. In humans, Resveratrol could potentially be a cure or treatment for Alzheimer’s Disease, cancer, cardiovascular disease and even spinal cord injuries.
It could also give benefits such as increased longevity, stroke damage protection, enhanced athletic performance, and also radiation exposure protection. No major side-effects have been documented, except for one case where excessive doses of the drug, injected into prepubescent mice, seemed to advance the growth of tumors. However, while there is a lack of documented side effects, it does not mean that there are none. The relative newness of the drug, coupled with lack of extensive testing means that there have not been many long-term observations.
For those who would like to experience the benefits of Resveratrol, they can drink red wine which contains only small doses of Resveratrol, or take supplements which would have much higher, concentrated doses.